Introduction and Objective:
In the context of the epidemic of type 2 diabetes (T2DM), a significant challenge from the perspective of public health is to effectively prevent this disease, which involves measures that inter alia halt the conversion of prediabetes to T2DM. The subject of the present part I of the two-module study is to analyze and synthesize the most important data concerning prediabetes. The paper presents the results of selected clinical studies which tested the effectiveness of interventions concerning lifestyle and pharmacotherapy in the prevention of T2DM in prediabetic patients.

Brief description of the current state of knowledge:
In light of the current state of knowledge, changes in lifestyle and the use of pharmacotherapy allow prevention of the conversion of prediabetes to T2DM. On account of the potential reversibility of prediabetes, an element of T2DM prevention programmes should be screening procedures in order to early diagnose its components, i.e. Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT). Special attention should be devoted by the clinician and the dietician to patients in whom IFG and IGT are jointly diagnosed, because, in order to delay the development of T2DM, they require aggressive intervention aimed at changing lifestyle, assisted by pharmacotherapy.

Recapitulation:
The implementation of effective methods of T2DM prevention is a chance to halt the rising wave of T2DM incidence. This question should be taken into account in the nationwide strategy for T2DM preventive measures. The next study will discuss in detail significant dietary recommendations, as well as indications for physical activity which can be applied in the treatment of prediabetes.