REVIEW PAPER
CARDIOPROTECTIVE EFFECT OF ESSENTIAL FATTY ACIDS
1
Z Wydziału Nauk o Zdrowiu Akademii Techniczno-Humanistycznej w Bielsku-Białej
Med Og. 2009;15(2):237-246
KEYWORDS
ABSTRACT
Unsaturated essential fatty acids (EFA): linoleic fatty acid (LA) of the omega-6 family and α-linolenic fatty acid (α-LA) from the group of omega-3 are necessary for the normal development and functioning of the body, although these acids are not subject to endogenous synthesis. For this reason, EFA must be delivered with food. Linoleic fatty acid (LA) and α-linolenic fatty acid (α-LA) are metabolised to long chain polyunsaturated fatty acids (LCPUFAs) while competing for enzymes. Some LCPUFAs are precursors for the synthesis of eicosanoids which, depending on a fatty acid, may perform a cardioprotective role. Eicosanoids of omega-3 family have an antiarryhytmic, antithrombotic, anti-inflammatory effect, lower the blood pressure, improve endothelial function, and blood lipid profile (effectively decrease the concentrations of plasma triacylogliceroles). However, excessive amounts of eicosanoids from omega-6 group may exert a procoagulative and proinflammatory effect.
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| eISSN: | 2084-4905 |
| ISSN: | 2083-4543 |
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